Dr. Arvid Lindau and discovery of von Hippel-Lindau disease

J Neurosurg. 2015 Oct;123(4):1093-7. doi: 10.3171/2015.1.JNS131963. Epub 2015 Mar 6.

Abstract

Arvid Lindau, MD, PhD, consolidated the disparate array of benign and malignant visceral and nervous system lesions into the neoplastic syndrome known as von Hippel-Lindau (VHL) disease. Based on this pioneering work, Dr. Lindau was awarded both a Rockefeller fellowship to work in Dr. Harvey Cushing's laboratory in Boston, Massachusetts, and the Lennmalm Prize. While working in Dr. Cushing's laboratory, Dr. Lindau continued his study of CNS hemangioblastomas. His work with Dr. Cushing led to their lifelong friendship and scientific collaboration. In this paper the authors describe Arvid Lindau's pioneering work in nervous system tumor pathology, his relationship to Dr. Cushing, and his role in advancing neurological surgery and research in Europe.

Keywords: Arvid Lindau; Harvey Cushing; VHL = von Hippel-Lindau; hemangioblastoma; history; von Hippel-Lindau disease.

Publication types

  • Biography
  • Historical Article
  • Portrait
  • Research Support, Non-U.S. Gov't

MeSH terms

  • History, 21st Century
  • Sweden
  • von Hippel-Lindau Disease / history*

Personal name as subject

  • Arvid Lindau