Isolated extraocular muscle infiltration with plasmacytoma treated with localized injection of dexamethasone

J Neuroophthalmol. 2015 Jun;35(2):168-70. doi: 10.1097/WNO.0000000000000221.

Abstract

Plasmacytoma of the orbit secondary to multiple myeloma is rare and has not previously been reported limited to an extraocular muscle. Conventional treatment is either localized radiotherapy or systemic chemotherapy. We report a case of plasmacytoma within the medial rectus muscle, which regressed completely with localized infiltration of dexamethasone.

MeSH terms

  • Aged
  • Antibodies, Monoclonal / metabolism
  • Antigens, CD / metabolism
  • Antineoplastic Agents, Hormonal / therapeutic use*
  • Dexamethasone / therapeutic use*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Melanocytes / metabolism
  • Melanocytes / pathology
  • Oculomotor Muscles / drug effects*
  • Oculomotor Muscles / physiopathology*
  • Plasmacytoma / drug therapy*
  • Tomography, X-Ray Computed

Substances

  • Antibodies, Monoclonal
  • Antigens, CD
  • Antineoplastic Agents, Hormonal
  • VS38 monoclonal antibody
  • Dexamethasone