Hypervirulent Klebsiella pneumoniae

Open Forum Infect Dis. 2014 Jun 2;1(1):ofu028. doi: 10.1093/ofid/ofu028. eCollection 2014 Mar.

Abstract

Hypervirulent strains of Klebsiella pneumoniae are associated with abscess formation, commonly hepatic, and metastatic spread, even in healthy patients. We describe a case of this clinical syndrome, genotypic and phenotypic features of the isolate, and briefly review epidemiology, clinical manifestations, and pathogenesis of this underappreciated syndrome.

Keywords: Klebsiella pneumoniae; hypermucoviscous; hypervirulence; virulence factors.