New onset of kaposi sarcoma in a human immunodeficiency virus-1-infected homosexual man, despite early antiretroviral treatment, sustained viral suppression, and immune restoration

Amrei von Braun; Dominique L Braun; Jivko Kamarachev; Huldrych F Günthard

doi:10.1093/ofid/ofu005

New onset of kaposi sarcoma in a human immunodeficiency virus-1-infected homosexual man, despite early antiretroviral treatment, sustained viral suppression, and immune restoration

Open Forum Infect Dis. 2014 Apr 17;1(1):ofu005. doi: 10.1093/ofid/ofu005. eCollection 2014 Mar.

Authors

Amrei von Braun¹, Dominique L Braun¹, Jivko Kamarachev², Huldrych F Günthard¹

Affiliations

¹ Divisions of Infectious Diseases and Hospital Epidemiology.
² Dermatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Abstract

This is a rare case of new onset Kaposi sarcoma in a man infected with human immunodeficiency virus (HIV) and receiving antiretroviral treatment since primary HIV infection, with normal CD4(+) cell count and suppressed viral load. The presentation questions the general understanding of Kaposi sarcoma as an acquired immune deficiency syndrome-defining disease occurring predominantly in severely immunocompromised patients infected with HIV.

Keywords: HHV-8 reactivation; Kaposi sarcoma; immune restoration; primary HIV infection.