1 Dept. of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO (C-HC); Dept.t of Mathematics, Tamkang University, Taipei, Taiwan (Y-CC); Dept. of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan (R-FT); Dept. of Health Care Management, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan (R-FT); and Mackay Medicine, Nursing and Management College, Taipei, Taiwan (R-FT).