Stability of cosmetic emulsion containing different amount of hemp oil

Int J Cosmet Sci. 2015 Aug;37(4):408-16. doi: 10.1111/ics.12211. Epub 2015 Mar 20.

Abstract

Objective: The aim of the study was to determine the optimal conditions, that is the content of hemp oil and time of homogenization to obtain stable dispersion systems.

Methods: For this purpose, six emulsions were prepared, their stability was examined empirically and the most correctly formulated emulsion composition was determined using a computer simulation. Variable parameters (oil content and homogenization time) were indicated by the optimization software based on Kleeman's method. Physical properties of the synthesized emulsions were studied by numerous techniques involving particle size analysis, optical microscopy, Turbiscan test and viscosity of emulsions.

Results: The emulsion containing 50 g of oil and being homogenized for 6 min had the highest stability. Empirically determined parameters proved to be consistent with the results obtained using the computer software. The computer simulation showed that the most stable emulsion should contain from 30 to 50 g of oil and should be homogenized for 2.5-6 min.

Conclusions: The computer software based on Kleeman's method proved to be useful for quick optimization of the composition and production parameters of stable emulsion systems. Moreover, obtaining an emulsion system with proper stability justifies further research extended with sensory analysis, which will allow the application of such systems (containing hemp oil, beneficial for skin) in the cosmetic industry.

Keywords: Turbiscan test; droplet size; emulsion; hemp oil; stability.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cannabis*
  • Cosmetics*
  • Drug Stability*
  • Emulsions*
  • Plant Oils / analysis*

Substances

  • Cosmetics
  • Emulsions
  • Plant Oils