Identification of novel Bromus- and Trifolium-associated circular DNA viruses

Arch Virol. 2015 May;160(5):1303-11. doi: 10.1007/s00705-015-2358-6. Epub 2015 Feb 21.

Abstract

The genomes of a large number of highly diverse novel circular DNA viruses from a wide range of sources have been characterised in recent years, including circular single-stranded DNA (ssDNA) viruses that share similarities with plant-infecting ssDNA viruses of the family Geminiviridae. Here, we describe six novel circular DNA viral genomes that encode replication-associated (Rep) proteins that are most closely related to those of either geminiviruses or gemycircularviruses (a new group of ssDNA viruses that are closely related to geminiviruses). Four possible viral genomes were recovered from Bromus hordeaceus sampled in New Zealand, and two were recovered from B. hordeaceus and Trifolium resupinatum sampled in France. Two of the viral genomes from New Zealand (one from the North Island and one from the South Island each) share >99 % sequence identity, and two genomes recovered from B. hordeaceus and T. resupinatum sampled in France share 74 % identity. All of the viral genomes that were recovered were found to have a major open reading frame on both their complementary and virion-sense strands, one of which likely encodes a Rep and the other a capsid protein. Although future infectivity studies are needed to identify the host range of these viruses, this is the first report of circular DNA viruses associated with grasses in New Zealand.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Bromus / virology*
  • Capsid Proteins / genetics
  • Cluster Analysis
  • DNA Helicases / genetics
  • DNA Viruses / classification*
  • DNA Viruses / genetics
  • DNA Viruses / isolation & purification
  • DNA, Circular / genetics*
  • DNA, Viral / chemistry
  • DNA, Viral / genetics*
  • France
  • Geminiviridae
  • Molecular Sequence Data
  • New Zealand
  • Open Reading Frames
  • Phylogeny
  • Plant Viruses / classification*
  • Plant Viruses / genetics
  • Plant Viruses / isolation & purification
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Sequence Homology
  • Trifolium / virology*

Substances

  • Capsid Proteins
  • DNA, Circular
  • DNA, Viral
  • DNA Helicases

Associated data

  • GENBANK/KM510189
  • GENBANK/KM510190
  • GENBANK/KM510191
  • GENBANK/KM510192
  • GENBANK/KP005453
  • GENBANK/KP005454