[Polymorphism of the CETP gene promoter region and its influence on protein activity in coronary heart disease]

L M Sharafetdinova; R K Ismagilova; E V Maĭkova; A A Podol'skaia; O A Kravtsova

[Polymorphism of the CETP gene promoter region and its influence on protein activity in coronary heart disease]

Tsitologiia. 2014;56(6):462-4.

[Article in Russian]

Authors

L M Sharafetdinova, R K Ismagilova, E V Maĭkova, A A Podol'skaia, O A Kravtsova

PMID: 25696989

Abstract

The paper shows the lack of association of two polymorphic loci localized in the promoter region of the gene CETP (rs1800775 and rs4783961) with the risk of coronary heart disease in the population of the Republic of Tatarstan. Also, there are no differences in the activity of the enzyme among the carriers of different genotypes.

Publication types

English Abstract
Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Case-Control Studies
Cholesterol Ester Transfer Proteins / genetics*
Cholesterol Ester Transfer Proteins / metabolism
Coronary Disease / enzymology
Coronary Disease / genetics*
Coronary Disease / pathology
Gene Frequency
Genetic Loci
Genotype
Heterozygote
Humans
Polymorphism, Genetic*
Promoter Regions, Genetic*
Risk
Tatarstan

Substances

CETP protein, human
Cholesterol Ester Transfer Proteins