Abstract
Structures of amyloid-beta peptides Aβ1-40, Aβ10-35, Aβ13-23 and Aβ16-22 in a complex with model membranes in solution were obtained on the analysis of NMR experimental data. It has been established that the process of peptide-micelle complex formation occurs through the amino acid residues L17, F19, F20 and G29-M35.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Amino Acids / chemistry*
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Amyloid beta-Peptides / chemical synthesis
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Amyloid beta-Peptides / chemistry*
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Deuterium
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Humans
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Magnetic Resonance Spectroscopy
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Membranes, Artificial
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Micelles
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Models, Molecular
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Molecular Sequence Data
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Peptide Fragments / chemical synthesis
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Peptide Fragments / chemistry*
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Protein Structure, Secondary
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Sodium Dodecyl Sulfate / chemistry*
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Solutions
Substances
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Amino Acids
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Amyloid beta-Peptides
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Membranes, Artificial
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Micelles
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Peptide Fragments
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Solutions
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amyloid beta-protein (1-40)
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amyloid beta-protein (10-35)
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amyloid beta-protein (16-22)
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Sodium Dodecyl Sulfate
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Deuterium