Identification of BRAF 3'UTR Isoforms in Melanoma

Andrea Marranci; Andrea Tuccoli; Marianna Vitiello; Elisa Mercoledi; Samanta Sarti; Simone Lubrano; Monica Evangelista; Antonella Fogli; Camilo Valdes; Francesco Russo; Massimo Dal Monte; Maria A Caligo; Marco Pellegrini; Enrico Capobianco; Nicholas Tsinoremas; Laura Poliseno

doi:10.1038/jid.2015.47

Identification of BRAF 3'UTR Isoforms in Melanoma

J Invest Dermatol. 2015 Jun;135(6):1694-1697. doi: 10.1038/jid.2015.47. Epub 2015 Feb 16.

Authors

Andrea Marranci¹, Andrea Tuccoli², Marianna Vitiello³, Elisa Mercoledi², Samanta Sarti³, Simone Lubrano³, Monica Evangelista⁴, Antonella Fogli⁵, Camilo Valdes⁶, Francesco Russo⁷, Massimo Dal Monte⁸, Maria A Caligo⁵, Marco Pellegrini⁹, Enrico Capobianco¹⁰, Nicholas Tsinoremas⁶, Laura Poliseno¹¹

Affiliations

¹ Oncogenomics Unit, Core Research Laboratory, Istituto Toscano Tumori, Pisa, Italy; Department of Biology, University of Pisa, Pisa, Italy.
² Oncogenomics Unit, Core Research Laboratory, Istituto Toscano Tumori, Pisa, Italy.
³ Oncogenomics Unit, Core Research Laboratory, Istituto Toscano Tumori, Pisa, Italy; University of Siena, Siena, Italy.
⁴ Institute of Clinical Physiology (IFC), CNR, Pisa, Italy.
⁵ Sezione di Genetica Oncologica, Dipartimento di Medicina di Laboratorio e Diagnostica Molecolare, Università di Pisa, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
⁶ Center for Computational Science, University of Miami, Miami, Florida, USA.
⁷ Laboratory of Integrative Systems Medicine (LISM), Institute of Informatics and Telematics (IIT) and Institute of Clinical Physiology (IFC), CNR, Pisa, Italy; Department of Computer Science, University of Pisa, Pisa, Italy.
⁸ Department of Biology, University of Pisa, Pisa, Italy.
⁹ Laboratory of Integrative Systems Medicine (LISM), Institute of Informatics and Telematics (IIT) and Institute of Clinical Physiology (IFC), CNR, Pisa, Italy.
¹⁰ Center for Computational Science, University of Miami, Miami, Florida, USA; Laboratory of Integrative Systems Medicine (LISM), Institute of Informatics and Telematics (IIT) and Institute of Clinical Physiology (IFC), CNR, Pisa, Italy.
¹¹ Oncogenomics Unit, Core Research Laboratory, Istituto Toscano Tumori, Pisa, Italy; Institute of Clinical Physiology (IFC), CNR, Pisa, Italy. Electronic address: laura.poliseno@gmail.com.

PMID: 25685929
DOI: 10.1038/jid.2015.47

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

3' Untranslated Regions
Alternative Splicing
Animals
Cell Line, Tumor
DNA, Complementary / metabolism
Exons
Gene Expression Regulation, Neoplastic*
Humans
Melanoma / genetics*
Melanoma / metabolism
Mice
Protein Isoforms / genetics
Protein Isoforms / metabolism
Proto-Oncogene Proteins B-raf / genetics*
Proto-Oncogene Proteins B-raf / metabolism
Rats
Skin Neoplasms / genetics*
Skin Neoplasms / metabolism

Substances

3' Untranslated Regions
DNA, Complementary
Protein Isoforms
BRAF protein, human
Proto-Oncogene Proteins B-raf