Enhancement of antioxidant effects of naringin after atmospheric pressure dielectric barrier discharge plasma treatment

Bioorg Med Chem Lett. 2015 Mar 15;25(6):1236-9. doi: 10.1016/j.bmcl.2015.01.054. Epub 2015 Jan 30.

Abstract

Naringin is the natural chief bitter flavonoid found in Citrus species. Herein, bitter naringin was treated with atmospheric pressure plasma to afford two new converted flavonoids, narinplasmins A (2) and B (3), along with the known compound, 2R-naringin. The structures of the two new naringin derivatives were elucidated on the basis of spectroscopic methods. The antioxidant activity of all isolates was evaluated based on 1,1-diphenyl-2-picrylhydrazyl and peroxynitrite (ONOO(-)) scavenging assays. The new flavanone glycoside 2 containing a methoxyalkyl group exhibited significantly improved antioxidant properties in these assays relative to the parent naringin.

Keywords: Alkylated flavonoid; Antioxidant; Atmospheric pressure plasma; Dielectric barrier discharge; Naringin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / chemistry*
  • Atmospheric Pressure
  • Circular Dichroism
  • Citrus / chemistry
  • Citrus / metabolism
  • Disaccharides / chemistry*
  • Flavanones / chemistry*
  • Flavonoids / chemistry
  • Magnetic Resonance Spectroscopy
  • Molecular Conformation
  • Peroxynitrous Acid / chemistry

Substances

  • Antioxidants
  • Disaccharides
  • Flavanones
  • Flavonoids
  • narinplasmin B
  • Peroxynitrous Acid
  • naringin