Rapamycin: a therapy of choice for endoplasmic reticulum stress-induced renal proximal tubule toxicity?

Toxicology. 2015 Apr 1:330:41-3. doi: 10.1016/j.tox.2015.02.001. Epub 2015 Feb 7.

Authors

Frank Thévenod¹, Wing-Kee Lee², Natascha A Wolff²

Affiliations

¹ Chair of Physiology, Pathophysiology & Toxicology, Centre for Biomedical Education and Research, Witten/Herdecke University, Stockumer Str. 12, 58453 Witten, Germany. Electronic address: frank.thevenod@uni-wh.de.
² Chair of Physiology, Pathophysiology & Toxicology, Centre for Biomedical Education and Research, Witten/Herdecke University, Stockumer Str. 12, 58453 Witten, Germany.

PMID: 25668123
DOI: 10.1016/j.tox.2015.02.001

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Survival / drug effects
Cell Survival / physiology
Endoplasmic Reticulum Stress / drug effects*
Endoplasmic Reticulum Stress / physiology
Fanconi Syndrome / chemically induced
Fanconi Syndrome / drug therapy*
Fanconi Syndrome / immunology
Humans
Immunosuppressive Agents / pharmacology
Immunosuppressive Agents / therapeutic use*
Kidney Tubules, Proximal / drug effects
Kidney Tubules, Proximal / immunology
Sirolimus / pharmacology
Sirolimus / therapeutic use*

Substances

Immunosuppressive Agents
Sirolimus