Adult neurogenesis has been well studied in hippocampus and subventricular zone (SVZ); while this is much less appreciated in other brain regions, including amygdala, hypothalamus, and piriform cortex (PC). The present review aims at summarizing recent advances on the occurrence of new neurons in the PC, their potential origin, and migration route from the SVZ. We further discuss the relevant implications in olfactory dysfunction accompanying the neurodegenerative diseases.
Keywords: Alzheimer’s disease; Parkinson’s disease; adult neurogenesis; degeneration; epilepsy; olfaction; piriform cortex.