Bokeh microscopy-enabled microfluidic channels for facile point-of-care monitoring

Biomed Microdevices. 2015 Feb;17(1):13. doi: 10.1007/s10544-014-9916-7.

Abstract

We report the implementation of the bokeh microscopy scheme in microfluidic settings for future applications in point-of-care microchannel monitoring in highly resource-limited environments. We realize the functional integration using a single polymer microlens fabricated over the microchannel. The inherent simplicity of the bokeh microscopy enables image capturing with an off-the-shelf camera. Our pilot devices exhibit 10 ∼ 40 of magnification and 67 ∼ 252 μm of field-of-view extent, confirming their utility for monitoring 50 ∼ 100 μm microchannels carrying 10 ∼ 50 μm objects.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Microfluidic Analytical Techniques / instrumentation*
  • Microfluidic Analytical Techniques / methods
  • Microscopy / instrumentation*
  • Microscopy / methods*
  • Point-of-Care Systems*