A surface-acoustic-wave-based cantilever bio-sensor

Biosens Bioelectron. 2015 Jun 15:68:570-576. doi: 10.1016/j.bios.2014.12.058. Epub 2014 Dec 30.

Abstract

A scalable surface-acoustic-wave- (SAW-) based cantilevered device for portable bio-chemical sensing applications is presented. Even in the current, proof-of-principle implementation this architecture is shown to outperform commercial quartz-crystal microbalances in terms of sensitivity. Adhesion of analytes on a functionalized surface of the cantilever shifts the resonant frequency of a SAW-generating transducer due to the stress-induced variation of the speed of surface acoustic modes. We discuss the relevance of this approach for diagnostics applications based on miniaturized devices.

Keywords: Cantilever bio-sensor; Surface acoustic wave.

MeSH terms

  • Biosensing Techniques / instrumentation*
  • Humans
  • Pathology, Molecular / instrumentation
  • Quartz Crystal Microbalance Techniques / instrumentation*
  • Sound*