Facile synthesis of magnetic homochiral metal-organic frameworks for "enantioselective fishing"

Chem Commun (Camb). 2015 Feb 28;51(17):3566-9. doi: 10.1039/c4cc09988e.

Abstract

Magnetic functionalized homochiral metal-organic frameworks (MOFs) were prepared and applied to efficient enantioselective fishing of chiral drug intermediates. Under optimized conditions, the enantiomeric excess (ee) value as high as 85.2% was achieved for methyl phenyl sulfoxide (MPS) within 3 min.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Magnetic Phenomena
  • Models, Molecular
  • Molecular Structure
  • Organometallic Compounds / chemical synthesis
  • Organometallic Compounds / chemistry*
  • Particle Size
  • Stereoisomerism
  • Sulfoxides / chemical synthesis*
  • Sulfoxides / chemistry
  • Surface Properties
  • Zinc / chemistry

Substances

  • Organometallic Compounds
  • Sulfoxides
  • methyl phenyl sulfoxide
  • Zinc