DNA-aptamer gating membranes

Chem Commun (Camb). 2015 Mar 28;51(25):5471-4. doi: 10.1039/c4cc09660f.

Abstract

This report describes a membrane barrier whose permeability is modulated through the recognition of a small-molecule target, adenosine triphosphate (ATP), by a DNA-aptamer. The gating function of the DNA-aptamer in the stimulus-responsive membrane was shown to be specific, concentration dependent, and reversible.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / metabolism*
  • Aptamers, Nucleotide / metabolism*
  • Particle Size
  • Permeability
  • Surface Properties

Substances

  • Aptamers, Nucleotide
  • Adenosine Triphosphate