A case of retinoblastoma metastasizing to the mandible and review of literature

Cranio. 2016 Mar;34(2):133-8. doi: 10.1179/2151090314Y.0000000032.

Abstract

Objectives: The aim of this case report and review was to determine the characteristics of retinoblastoma.

Methods: One case report was introduced along with previous reports on retinoblastoma metastasizing to the mandible.

Results: Sixteen cases from 14 reports were included in this study. Including the present case, 11 of 16 patients died within 8 months.

Discussion: Retinoblastoma rarely metastasizes to the mandible. However, metastasis to other organs should be considered, and specialists should be consulted if retinoblastoma metastasis to the mandible is observed. Moreover, it is necessary to follow up patients after multidisciplinary therapy is completed, because subsequent complications of the teeth and jawbones associated with therapy could occur.

Keywords: Mandible; Metastasis; Multidisciplinary therapy; Peripheral blood stem cell transplantation; Retinoblastoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child, Preschool
  • Combined Modality Therapy
  • Humans
  • Male
  • Mandibular Neoplasms / diagnostic imaging
  • Mandibular Neoplasms / secondary*
  • Mandibular Neoplasms / therapy
  • Retinal Neoplasms / pathology*
  • Retinoblastoma / diagnostic imaging
  • Retinoblastoma / secondary*
  • Retinoblastoma / therapy
  • Treatment Outcome