Abstract
New neurons are continuously generated in specific regions in the adult brain. Studies in rodents have demonstrated that adult-born neurons have specific functional features and mediate neural plasticity. Data on the extent and dynamics of adult neurogenesis in adult humans are starting to emerge, and there are clear similarities and differences compared to other mammals. Why do these differences arise? And what do they mean?
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Animals
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Biological Evolution
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Corpus Striatum / physiology
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Hippocampus / physiology
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Humans
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Lateral Ventricles / physiology
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Models, Neurological
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Neocortex / physiology
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Neurogenesis*
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Neuronal Plasticity
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Olfactory Bulb / physiology
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Organ Specificity
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Transcriptome
Grants and funding
Work in the authors’ laboratory was supported by grants from the Swedish Research Council, the Swedish Cancer Society, the Karolinska Institute, Tobias Stiftelsen, AFA Försäkringar, the Swedish Foundation for Strategic Research, the Strategic Research Programme in Stem Cells and Regenerative Medicine at Karolinska Institutet (StratRegen), the ERC, Torsten Söderbergs Stiftelse and Knut och Alice Wallenbergs Stiftelse. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.