Pertussis in the newborn: certainties and uncertainties in 2014

Gustavo Rocha; Paulo Soares; Henrique Soares; Susana Pissarra; Hercília Guimarães

doi:10.1016/j.prrv.2014.01.004

Pertussis in the newborn: certainties and uncertainties in 2014

Paediatr Respir Rev. 2015 Mar;16(2):112-8. doi: 10.1016/j.prrv.2014.01.004. Epub 2014 Jan 31.

Authors

Gustavo Rocha¹, Paulo Soares², Henrique Soares², Susana Pissarra², Hercília Guimarães²

Affiliations

¹ Division of Neonatology, Department of Pediatrics, Hospital de São João, Porto, Portugal. Electronic address: gusrocha@oninet.pt.
² Division of Neonatology, Department of Pediatrics, Hospital de São João, Porto, Portugal.

PMID: 25613084
DOI: 10.1016/j.prrv.2014.01.004

Abstract

Bordetella pertussis infection remains a serious potential health risk to infants, specially in those too young to be vaccinated. Over the recent years, numerous sources highlighted a widespread resurgence, making it, again, a challenging disease. Globally, pertussis is ranked among the 10 leading causes of childhood mortality. This review summarizes the most recent literature and will address the most important aspects that pediatricians and neonatologists must be familiar with, when treating a newborńs pertussis infection.

Keywords: Antibiotic resistance; Bordetella pertussis; epidemiology; hyperleukocytosis; laboratory diagnosis; newborn; pulmonary hypertension; vaccination..

Publication types

Review

MeSH terms

Anti-Bacterial Agents / therapeutic use*
Bordetella pertussis*
Humans
Infant, Newborn
Pertussis Vaccine / administration & dosage*
Whooping Cough / complications*
Whooping Cough / diagnosis
Whooping Cough / drug therapy

Substances

Anti-Bacterial Agents
Pertussis Vaccine