Purpuric bullous pemphigoid

Am J Dermatopathol. 2015 Feb;37(2):e18-20. doi: 10.1097/DAD.0000000000000057.

Abstract

Rare clinical variants of bullous pemphigoid (BP) include vesicular BP, dyshidrosiform BP, pemphigoid nodularis, seborrheic BP, pemphigoid vegetans, localized BP, erythrodermic BP, and juvenile BP. To our knowledge, this is the first report of an unusual case of purpuric BP. We present a case of 85-year-old white man who presented with a 2-week history of blisters and pruritic urticarial lesions all over his body. The diagnosis of purpuric BP was made on the basis of history, clinical presentation, histopathology report, direct and indirect immunofluorescence studies the diagnosis of purpuric BP was made. The reason for the development of palmoplantar purpuric lesions concomitant to ordinary patches and plaques of BP is unknown.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Biopsy
  • Dapsone / administration & dosage
  • Diagnosis, Differential
  • Drug Administration Schedule
  • Drug Therapy, Combination
  • Fluorescent Antibody Technique
  • Glucocorticoids / administration & dosage
  • Humans
  • Male
  • Pemphigoid, Bullous / diagnosis*
  • Pemphigoid, Bullous / drug therapy
  • Pemphigoid, Bullous / pathology
  • Predictive Value of Tests
  • Prednisolone / administration & dosage
  • Purpura / diagnosis*
  • Purpura / drug therapy
  • Purpura / pathology
  • Skin / drug effects
  • Skin / pathology*
  • Treatment Outcome

Substances

  • Glucocorticoids
  • Dapsone
  • Prednisolone