[GADV]-protein world hypothesis on the origin of life

Orig Life Evol Biosph. 2014 Dec;44(4):299-302. doi: 10.1007/s11084-014-9383-4. Epub 2015 Jan 16.

Abstract

RNA world hypothesis is widely accepted still now, as an idea by which the origin of life might be explained. But, there are many weak points in the hypothesis. In contrast, I have proposed a more reasonable [GADV]-protein world hypothesis or GADV hypothesis, suggesting that life originated from the protein world, which was formed by pseudo-replication of [GADV]-proteins. In this communication, I will discuss about the origin of life from the point of view of the GADV hypothesis.

MeSH terms

  • Alanine / chemistry
  • Alanine / metabolism
  • Aspartic Acid / chemistry
  • Aspartic Acid / metabolism
  • Biological Evolution
  • Carbon / metabolism
  • Genetic Code*
  • Glycine / chemistry
  • Glycine / metabolism
  • Models, Genetic*
  • Origin of Life*
  • Protein Biosynthesis*
  • Protein Conformation
  • Protein Folding
  • RNA, Transfer, Amino Acid-Specific / chemistry*
  • RNA, Transfer, Amino Acid-Specific / metabolism
  • Valine / chemistry
  • Valine / metabolism

Substances

  • RNA, Transfer, Amino Acid-Specific
  • Aspartic Acid
  • Carbon
  • Valine
  • Alanine
  • Glycine