Efficacy of jollab in the treatment of depression in dyspeptic patients: a randomized double-blind controlled trial

J Evid Based Complementary Altern Med. 2015 Apr;20(2):104-8. doi: 10.1177/2156587214563542. Epub 2015 Jan 13.

Abstract

The current study aimed to evaluate the efficacy of jollab, a well-known beverage from traditional Persian medicine in the treatment of depression among patients suffering from functional dyspepsia. In a randomized, double-blind, placebo-controlled trial, a pair of 80 patients were enrolled in 2 parallel groups as Jollab and placebo. The Beck Depression Inventory-II questionnaire was used for the assessment. At all, 133 patients enrolling in the treatment and placebo groups ended the protocol. According to the outcomes, changes in scores between the 2 groups were statistically significant at the end of trial (P ≤ .001). Taken as a whole, treatment group was significantly more effective than the placebo. Focusing on nutritional and pharmaceutical properties, jollab may be introduced not only as a medication for depression and allied ailment but also a pleasant daily drink.

Keywords: functional dyspepsia; jollab; major depressive disorder; traditional Persian medicine.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Beverages
  • Depressive Disorder, Major / complications*
  • Depressive Disorder, Major / drug therapy*
  • Depressive Disorder, Major / epidemiology
  • Dyspepsia / complications*
  • Female
  • Humans
  • Iran / epidemiology
  • Male
  • Medicine, Traditional / methods*
  • Middle Aged
  • Surveys and Questionnaires