Draft Genome Sequence of Actinoplanes utahensis NRRL 12052, a Microorganism Involved in Industrial Production of Pharmaceutical Intermediates

Rodrigo Velasco-Bucheli; Carlos Del Cerro; Daniel Hormigo; Carmen Acebal; Miguel Arroyo; José L García; Isabel de la Mata

doi:10.1128/genomeA.01411-14

Draft Genome Sequence of Actinoplanes utahensis NRRL 12052, a Microorganism Involved in Industrial Production of Pharmaceutical Intermediates

Genome Announc. 2015 Jan 8;3(1):e01411-14. doi: 10.1128/genomeA.01411-14.

Authors

Rodrigo Velasco-Bucheli¹, Carlos Del Cerro², Daniel Hormigo¹, Carmen Acebal¹, Miguel Arroyo¹, José L García², Isabel de la Mata³

Affiliations

¹ Department of Biochemistry and Molecular Biology I, Facultad de Biología, Universidad Complutense de Madrid, Madrid, Spain.
² Department of Environmental Biology, Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
³ Department of Biochemistry and Molecular Biology I, Facultad de Biología, Universidad Complutense de Madrid, Madrid, Spain idlmata@ucm.es.

Abstract

Here, we describe the draft genome sequence of Actinoplanes utahensis NRRL 12052, a filamentous bacterium that encodes an aculeacin A acylase and a putative N-acyl-homoserine lactone acylase of biotechnological interest. Moreover, several nonribosomal peptide synthase (NRPS) and polyketide synthase (PKS) clusters and antibiotic resistance genes have been identified.