Abstract
We report a one-step synthetic strategy for the preparation of recombinant protein (EGFP-Protein G)-coated PbS quantum dots for dual (visible and second-NIR) fluorescence imaging of breast tumors at the cellular and whole-body level.
MeSH terms
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Animals
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Breast Neoplasms / metabolism*
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Breast Neoplasms / pathology*
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Cell Line, Tumor
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Coated Materials, Biocompatible / chemical synthesis
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Green Fluorescent Proteins / chemistry*
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Green Fluorescent Proteins / genetics
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Humans
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Image Enhancement / methods
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Infrared Rays
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Lead / chemistry*
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Lead / radiation effects
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Mice
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Mice, Nude
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Microscopy, Fluorescence, Multiphoton / methods*
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Quantum Dots*
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Recombinant Proteins / pharmacokinetics
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Reproducibility of Results
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Selenium Compounds / chemistry*
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Selenium Compounds / radiation effects
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Sensitivity and Specificity
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Whole Body Imaging / methods
Substances
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Coated Materials, Biocompatible
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Recombinant Proteins
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Selenium Compounds
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enhanced green fluorescent protein
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lead selenide
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Green Fluorescent Proteins
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Lead