[Variants of the immunoreactivity and infectious process in bank vole (Myodes glareolus) experimentally infected with the hantavirus Puumala (PUUV)]

Vopr Virusol. 2014 Jul-Aug;59(4):42-6.
[Article in Russian]

Abstract

As a result of a longitudinal study of the Puumala hantavirus (PUUV) in the experimentally infected bank voles (Myodes glareolus), we revealed three groups of the voles differing in the immunoreactivity and viral antigen concentration in the organs. The close correlation between these parameters suggested the existence of various mechanisms of the hantavirus persistence in the host.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Antibody Formation / immunology*
  • Antigens, Viral / immunology*
  • Arvicolinae / virology
  • Hemorrhagic Fever with Renal Syndrome / pathology
  • Hemorrhagic Fever with Renal Syndrome / virology
  • Orthohantavirus / genetics
  • Orthohantavirus / immunology*
  • Orthohantavirus / pathogenicity
  • Phylogeny
  • Puumala virus / genetics
  • Puumala virus / immunology*
  • Puumala virus / pathogenicity
  • Rodent Diseases / virology

Substances

  • Antigens, Viral