Abstract
The present review deals with the sol-gel imprinting of both drug and non-drug templates of medical relevance, namely neurotransmitters, biomarkers, hormones, proteins and cells. Nearly a hundred recent works, either developmental or applied in a medical-related context, were critically analyzed. It may be concluded that, although research is still at an early stage, the potential of these sol-gel materials was well demonstrated in a few applications of critical interest for medicinal/biomedical science. The vast room left for expansion and improvement envisages a continuously growing interest by researchers in the future, eventually resulting in important medical applications able to enter the professional and consumer medical markets.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / metabolism
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Anti-Inflammatory Agents, Non-Steroidal / chemistry
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Anti-Inflammatory Agents, Non-Steroidal / metabolism
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Biomarkers / chemistry
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Biomarkers / metabolism
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Cells, Immobilized
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Chemistry, Pharmaceutical / methods*
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Drug Carriers / chemical synthesis
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Drug Carriers / chemistry
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Hormones / chemistry
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Hormones / metabolism
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Humans
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Molecular Imprinting / methods*
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Nafcillin / chemistry
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Nafcillin / metabolism
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Neurotransmitter Agents / chemistry
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Neurotransmitter Agents / metabolism
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Phase Transition*
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Psychotropic Drugs / chemistry
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Psychotropic Drugs / metabolism
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Quaternary Ammonium Compounds / chemistry
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Siloxanes / chemistry
Substances
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Anti-Bacterial Agents
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Anti-Inflammatory Agents, Non-Steroidal
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Biomarkers
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Drug Carriers
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Hormones
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Neurotransmitter Agents
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Psychotropic Drugs
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Quaternary Ammonium Compounds
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Siloxanes
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Nafcillin