Low Prevalence of Parvovirus 4 in HIV-infected Children in Denmark

Pediatr Infect Dis J. 2015 Jul;34(7):761-2. doi: 10.1097/INF.0000000000000642.

Abstract

Parvovirus 4 (PARV4) has been associated with HIV infection in adults. We examined plasma samples from 46 HIV-infected 0-year-old to 16-year-old children for the presence of PARV4. Four children (8.7%) had detectable PARV4 IgG and 1 had IgM. The result of PARV4 polymerase chain reaction was found to be negative in all patients. PARV4 seropositivity was associated with low CD4 count but not with HIV viral load.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Antibodies, Viral / blood
  • CD4 Lymphocyte Count
  • Child
  • Child, Preschool
  • Cohort Studies
  • Coinfection / epidemiology*
  • Coinfection / virology*
  • Denmark / epidemiology
  • Female
  • HIV Infections / complications*
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Infant
  • Male
  • Parvoviridae Infections / epidemiology*
  • Parvoviridae Infections / virology*
  • Parvovirus / classification*
  • Parvovirus / isolation & purification*
  • Seroepidemiologic Studies

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Immunoglobulin M