Highly oxygenated sesquiterpenes in Artemisia alba Turra

Phytochemistry. 2015 Feb:110:140-9. doi: 10.1016/j.phytochem.2014.12.008. Epub 2014 Dec 23.

Abstract

Ten new sesquiterpene alcohols of which seven germacranes, a eudesmane, a guaiane and an oplopane were isolated from the aerial parts of Artemisia alba Turra. Their structures and relative stereochemistry were elucidated by spectral methods ((1)H and (13)C NMR, COSY, HSQC, HMBC, NOESY, and MS). In addition, the known 7-hydroxycadin-4-en-3-one, centaureidin and axillarin were found for the first time in the studied species.

Keywords: Artemisia alba; Asteraceae; Eudesmane; Germacranes; Guaiane; Oplopane; Sesquiterpenes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcohols / chemistry
  • Artemisia / chemistry*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Oxygen / chemistry*
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes, Eudesmane / chemistry
  • Sesquiterpenes, Eudesmane / isolation & purification*
  • Sesquiterpenes, Guaiane / chemistry
  • Sesquiterpenes, Guaiane / isolation & purification*

Substances

  • Alcohols
  • Sesquiterpenes
  • Sesquiterpenes, Eudesmane
  • Sesquiterpenes, Guaiane
  • guaiane
  • eudesmane
  • Oxygen