How great is the threat of chikungunya virus?

Expert Rev Anti Infect Ther. 2015 Mar;13(3):291-3. doi: 10.1586/14787210.2015.995634. Epub 2014 Dec 24.

Abstract

In the last decade, chikungunya virus has emerged from an obscure arbovirus that caused limited outbreaks of disease in Africa and Asia to the cause of a pandemic affecting millions of people and spanning five continents. Two separate chikungunya virus genotypes have been responsible for outbreaks during this period, including strains adapted to transmission in Aedes albopictus mosquitoes. Further spread of this virus into new regions of the Western Hemisphere is predicted during the present rainy season in the tropics, and recurrent viral introductions and disease outbreaks, as occurred in Réunion in 2010, should be expected. Chikungunya virus no longer simply threatens; it has arrived as a significant, global pathogen.

Keywords: Aedes albopictus; alphavirus; arbovirus; chikungunya virus; emerging infectious diseases.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Aedes / virology*
  • Africa / epidemiology
  • Animals
  • Arboviruses / classification
  • Arboviruses / pathogenicity
  • Asia / epidemiology
  • Chikungunya Fever / epidemiology*
  • Chikungunya virus / genetics*
  • Chikungunya virus / pathogenicity
  • Communicable Diseases, Emerging
  • Disease Outbreaks
  • Humans
  • Insect Vectors / virology*