[The ameliorate effect of anthocyanin onMouse testis damage]

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2014 Oct;32(10):762-4.
[Article in Chinese]

Abstract

Objective: To study the effect of Anthocyanin (Ay) on Cadmium-Induced Mouse testis Damage.

Methods: Mouse testis damage model were constructed and testis malonaldehyde (MDA) and protein carbonxyl content (PCO), as well as catalase (CAT) and superoxide dismutase (SOD) were determined.

Results: The intoxication of cadmium can cause the increase of MDA and PCO content in mouse testis (P < 0.05), however, the activities of SOD and CAT were altered (P < 0.01).

Conclusion: Ay have the strong potent to scavenge free radicals, owing to its special chemical structures, and act as a protector to inhibit the oxidative stress induced by cadmium.

MeSH terms

  • Animals
  • Anthocyanins / chemistry
  • Anthocyanins / pharmacology*
  • Cadmium / toxicity*
  • Catalase / drug effects
  • Male
  • Malondialdehyde / analysis
  • Mice
  • Oxidative Stress
  • Protein Carbonylation / drug effects
  • Superoxide Dismutase / drug effects
  • Testis / drug effects*

Substances

  • Anthocyanins
  • Cadmium
  • Malondialdehyde
  • Catalase
  • Superoxide Dismutase