Correlation between umbilical cord hemoglobin and rate of jaundice requiring phototherapy in healthy newborns

Pediatr Int. 2015 Aug;57(4):626-8. doi: 10.1111/ped.12583. Epub 2015 Mar 25.

Abstract

Background: Delay of umbilical cord clamping by at least 1 min is recommended for newborns not requiring resuscitation in the International Liaison Committee On Resuscitation-Consensus on Science with Treatment Recommendations (ILCOR-CoSTR) 2010 guidelines. The delay in clamping improves iron status through early infancy but may increase the likelihood of jaundice requiring phototherapy. The present study investigated the relationship between umbilical cord hemoglobin and the rate of jaundice requiring phototherapy in healthy Japanese newborns.

Methods: Cord hemoglobin was measured in healthy newborns and the rate of infants receiving phototherapy for jaundice and other data were obtained from medical records.

Results: Jaundice requiring phototherapy mostly occurred in association with high cord blood hemoglobin, which is increased by delayed cord clamping.

Conclusions: Higher cord hemoglobin may increase neonatal jaundice in newborns in Japan, therefore the present results support the Japan Resuscitation Council guideline 2010, which does not recommend delay of umbilical cord clamping by at least 1 min, in contrast to the ILCOR guidelines.

Keywords: delayed umbilical cord clamping; neonatal jaundice; newborn; phototherapy.

MeSH terms

  • Female
  • Fetal Blood / metabolism*
  • Follow-Up Studies
  • Hemoglobins / metabolism*
  • Humans
  • Incidence
  • Infant, Newborn
  • Japan / epidemiology
  • Jaundice, Neonatal / blood*
  • Jaundice, Neonatal / epidemiology
  • Jaundice, Neonatal / therapy
  • Male
  • Phototherapy / methods*
  • Reference Values
  • Retrospective Studies
  • Time Factors
  • Umbilical Cord

Substances

  • Hemoglobins