DNA methylation is a key factor in understanding differentiation phenotype in esophageal squamous cell carcinoma

Epigenomics. 2014;6(6):567-9. doi: 10.2217/epi.14.56.
No abstract available

Keywords: cancer stem cell; differentiation; esophageal squamous cell carcinoma; methylation; transcription factor.

Publication types

  • Editorial

MeSH terms

  • Basic Helix-Loop-Helix Transcription Factors / genetics*
  • Carcinoma, Squamous Cell / genetics
  • Carcinoma, Squamous Cell / pathology*
  • DNA Methylation*
  • Epigenesis, Genetic
  • Esophageal Neoplasms / genetics
  • Esophageal Neoplasms / pathology*
  • Esophageal Squamous Cell Carcinoma
  • Gene Expression Regulation, Neoplastic
  • Homeodomain Proteins / genetics*
  • Humans
  • Prognosis

Substances

  • Basic Helix-Loop-Helix Transcription Factors
  • Homeodomain Proteins
  • SIM2 protein, human
  • SIX1 protein, human