No abstract available
Keywords:
TLR4; Type 1 diabetes; immune tolerization; innate immune therapy; reversal of Type 1 diabetes.
Publication types
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Editorial
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adaptive Immunity / drug effects
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Animals
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Antibodies, Monoclonal / therapeutic use*
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Diabetes Mellitus, Type 1 / immunology
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Diabetes Mellitus, Type 1 / therapy*
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Disease Models, Animal
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Humans
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Hygiene Hypothesis
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Immunity, Innate* / drug effects
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Inflammation Mediators / metabolism
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Insulin-Secreting Cells / drug effects*
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Insulin-Secreting Cells / immunology
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Mice, Inbred NOD
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Mice, Knockout
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Molecular Targeted Therapy
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Myeloid Differentiation Factor 88 / metabolism
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Toll-Like Receptor 4 / genetics
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Toll-Like Receptor 4 / immunology
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Toll-Like Receptor 4 / metabolism*
Substances
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Antibodies, Monoclonal
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Inflammation Mediators
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Myeloid Differentiation Factor 88
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TLR4 protein, human
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Toll-Like Receptor 4