Quality of life among breast cancer patients undergoing treatment in national cancer centers in Nepal

Asian Pac J Cancer Prev. 2014;15(22):9753-7. doi: 10.7314/apjcp.2014.15.22.9753.

Abstract

Purpose: To study the quality of life and to identify associated factors among breast cancer patients undergoing treatment in national cancer centers in Nepal.

Materials and methods: One hundred breast cancer patients were selected and interviewed using a structured questionnaire. European Organization of Research and Treatment of Cancer EORTC-QLQ-C30 and EORTC-QLQ-BR23 were used to assess quality of life and modified Medical Outcome Study -Social Support survey(mMOS-SS) was used to assess social support. Only multi-item scales of EORTC C30 and BR23 were analyzed for relationships. Independent sample T-tests and ANOVA were applied to analyze differences in mean scores.

Results: The score of global health status/quality of life (GHS/GQoL) was marginally above average (mean=52.8). The worst performed scales in C-30 were emotional and social function while best performed scales were physical and role function. In BR-23, most of the patients fell into the problematic group regarding sexual function and enjoyment. Almost 90% had financial difficulties. Symptom scales did not demonstrate many problems. Older individuals, patients with stage I breast cancer and thosewith good social support were found to have good GHS/GQoL. Of all the influencing factors, social support was established to have strong statistical associations with most of the functional scales: GHS/GQoL (0.003), emotional function (<0.001), cognitive function (0.020), social function (<0.001) and body image function (0.011). Body image was significantly associated with most of the influencing factors: monthly family income (0.003), type of treatment (<0.001), type of surgery (<0.001), stage of cancer (0.017) and social support (0.011).

Conclusions: Strategies to improve social support of the patients undergoing treatment should be given priority and financial difficulties faced by breast cancer patients should be well addressed from a policy making level by initiating health financing system.

MeSH terms

  • Breast Neoplasms / psychology*
  • Breast Neoplasms / therapy*
  • Combined Modality Therapy
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Health Status
  • Humans
  • Middle Aged
  • Neoplasm Staging
  • Nepal / epidemiology
  • Prognosis
  • Psychometrics
  • Quality of Life*
  • Surveys and Questionnaires