Multifunctional magnetic and fluorescent core-shell nanoparticles for bioimaging

Nanoscale. 2015 Feb 7;7(5):1606-9. doi: 10.1039/c4nr06104g.

Abstract

Novel magnetic and fluorescent core-shell nanoparticles have been fabricated, which exhibit superparamagnetic behavior and emit strong near-infrared fluorescence. The nanoparticles are highly biocompatible and can be internalized into cells with nucleic accumulation via strong interaction with nucleic acids, implying potential applications in the biomedical field.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials / chemistry
  • Biocompatible Materials / metabolism
  • Biocompatible Materials / toxicity
  • Carbocyanines / chemistry
  • Cell Line
  • Cell Nucleus / metabolism
  • Cell Survival / drug effects
  • Ferrosoferric Oxide / chemistry
  • Fluorescent Dyes / chemistry
  • Fluorescent Dyes / metabolism*
  • Humans
  • Magnetics*
  • Microscopy, Confocal
  • Nanoparticles / chemistry
  • Nanoparticles / metabolism*
  • Nanoparticles / toxicity
  • Silicon Dioxide / chemistry

Substances

  • Biocompatible Materials
  • Carbocyanines
  • Fluorescent Dyes
  • cyanine dye 5
  • Silicon Dioxide
  • Ferrosoferric Oxide