Enhancing antibacterium and strength of cellulosic paper by coating triclosan-loaded nanofibrillated cellulose (NFC)

Carbohydr Polym. 2015 Mar 6:117:996-1001. doi: 10.1016/j.carbpol.2014.10.014. Epub 2014 Oct 18.

Abstract

The nanofibrillated cellulose (NFC) was used as substrates to carry triclosan (TCS), which was then applied as a coating agent for impacting antibacterial property to paper while also improving its strength. The TCS-loaded NFC material was further characterized. UV-vis spectra results showed that a characteristic absorption band at 282 nm was observed, which was attributed to triclosan, confirming its successful loading onto NFC. The antibacterial activity tests indicated that the coated paper exhibited excellent antibacterial activity against Escherichia coli, and the growth inhibition of bacteria (GIB) increased as the loading amount of triclosan coated on paper increased. The GIB can reach 98.7% when the 0.023 g TCS-loaded NFC was coated on paper. Meanwhile, the tensile and tear index of the coated paper increased by 18.0% and 26.4%, respectively compared to the blank paper. Therefore, the triclosan-loaded paper could be potentially used in the medical field.

Keywords: Antibacterium; Nanofibrillated cellulose; Paper; Strength; Triclosan.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology*
  • Cellulose / chemistry*
  • Escherichia coli / drug effects
  • Hydrophobic and Hydrophilic Interactions
  • Nanofibers / chemistry*
  • Paper*
  • Structure-Activity Relationship
  • Temperature
  • Triclosan / chemistry*

Substances

  • Anti-Bacterial Agents
  • Triclosan
  • Cellulose