A promising CpG adjuvant-loaded nanoparticle-based vaccine for treatment of dust mite allergies

Immunotherapy. 2014;6(11):1161-3. doi: 10.2217/imt.14.97.
No abstract available

Keywords: CpG; Der p2; PLGA; allergy; asthma; biodegradable; house dust mite allergens; nanoparticles.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Antigens, Dermatophagoides / chemistry
  • Antigens, Dermatophagoides / immunology*
  • Arthropod Proteins / chemistry
  • Arthropod Proteins / immunology*
  • Chemotherapy, Adjuvant
  • Child
  • CpG Islands / genetics
  • Drug Delivery Systems
  • Humans
  • Hypersensitivity / immunology
  • Hypersensitivity / therapy*
  • Immunotherapy, Active*
  • Mice
  • Nanoparticles / administration & dosage*
  • Nanoparticles / chemistry
  • Oligonucleotides / administration & dosage*
  • Oligonucleotides / chemistry
  • Oligonucleotides / genetics
  • Particle Size
  • Pyroglyphidae / immunology
  • Th1 Cells / immunology*
  • Th1-Th2 Balance
  • Th2 Cells / immunology*

Substances

  • Antigens, Dermatophagoides
  • Arthropod Proteins
  • Dermatophagoides pteronyssinus antigen p 2
  • Oligonucleotides