Graphitic carbon in a nanostructured titanium oxycarbide thin film to improve implant osseointegration

Mater Sci Eng C Mater Biol Appl. 2015 Jan:46:409-16. doi: 10.1016/j.msec.2014.10.073. Epub 2014 Oct 28.

Abstract

A nanostructured coating layer on titanium implants, able to improve their integration into bones and to protect against the harsh conditions of body fluids, was obtained by Ion Plating Plasma Assisted, a method suitable for industrial applications. A titanium carbide target was attached under vacuum to a magnetron sputtering source powered with a direct current in the 500-1100 W range, and a 100 W radio frequency was applied to the sample holder. The samples produced at 900 W gave the best biological response in terms of overexpression of some genes of proteins involved in bone turnover. We report the characterization of a reference and of an implant sample, both obtained at 900 W. Different micro/nanoscopic techniques evidenced the morphology of the substrates, and X-ray Photoelectron Spectroscopy was used to disclose the surface composition. The layer is a 500 nm thick hard nanostructure, composed of 60% graphitic carbon clustered with 15% TiC and 25% Ti oxides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials
  • Carbon*
  • Cells, Cultured
  • Graphite*
  • Humans
  • Microscopy, Atomic Force
  • Microscopy, Electron, Scanning
  • Nanostructures*
  • Osseointegration*
  • Photoelectron Spectroscopy
  • Prostheses and Implants*
  • Surface Properties
  • Titanium*

Substances

  • Biocompatible Materials
  • Carbon
  • Graphite
  • Titanium