Polymorphism at BCL11A compared to HBS1L-MYB loci explains less of the variance in HbF in patients with sickle cell disease in Cameroon

Blood Cells Mol Dis. 2015 Mar;54(3):268-9. doi: 10.1016/j.bcmd.2014.11.010. Epub 2014 Nov 25.

Authors

Valentina Josiane Ngo Bitoungui¹, Jeanne Ngogang¹, Ambroise Wonkam²

Affiliations

¹ Department of Microbiology, Parasitology & Haematology, Faculty of Medicine & Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
² Division of Human Genetics, Faculty of Health Sciences, University of Cape Town (UCT), South Africa. Electronic address: ambroise.wonkam@uct.ac.za.

PMID: 25488618
DOI: 10.1016/j.bcmd.2014.11.010

No abstract available

Publication types

Comparative Study
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Anemia, Sickle Cell / epidemiology
Anemia, Sickle Cell / genetics*
Cameroon / epidemiology
Carrier Proteins / genetics*
Child
Child, Preschool
Female
Fetal Hemoglobin / genetics*
GTP-Binding Proteins / genetics*
Genes, myb*
Genetic Loci
HSP70 Heat-Shock Proteins / genetics*
Humans
Male
Nuclear Proteins / genetics*
Peptide Elongation Factors / genetics*
Polymorphism, Genetic
Repressor Proteins
Young Adult

Substances

BCL11A protein, human
Carrier Proteins
HSP70 Heat-Shock Proteins
Nuclear Proteins
Peptide Elongation Factors
Repressor Proteins
Fetal Hemoglobin
GTP-Binding Proteins
HBS1L protein, human