Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance

Haematologica. 2015 Apr;100(4):e132-6. doi: 10.3324/haematol.2014.112995. Epub 2014 Dec 5.
No abstract available

Keywords: RAS; clonal mutations; pediatric acute lymphoblastic leukemia; prednisolone resistance.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Child
  • Drug Resistance, Neoplasm
  • Genes, ras*
  • Humans
  • Mutation*
  • Precision Medicine
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Prednisolone / administration & dosage
  • Prednisolone / therapeutic use

Substances

  • Prednisolone