The impact of preemptive ropivacaine in inguinal hernioplasty--a randomized controlled trial

Int J Surg. 2015 Jan:13:76-79. doi: 10.1016/j.ijsu.2014.11.037. Epub 2014 Dec 3.

Abstract

Introduction: This study was aimed to assess the outcome of Ilioinguinal, Iliohypogastric block and wound infiltration with 0.75% ropivacaine on pain perception, first analgesic request and hospital stay following inguinal Lichtenstein mesh repair.

Method: This was a prospective, randomized, double-blind study with 60 patients undergoing inguinal hernioplasty under general anesthesia. Patients were randomly allocated to one of the two groups by the sealed envelope method. Group 1 (n=30) received nerve blocks and incision infiltration with 0.75% ropivacaine while group 2 (n=30) received isotonic saline. Postoperatively pain intensity, time of demand for the first analgesic and duration of hospital stay were assessed.

Results: Median Visual Analog Scale (VAS) score of group 1 was 4 (high=6, low=3) while for group 2 was 5.50 (high=8, low=4) and the p value was <0.001. Mean time for the demand of the first analgesic was prolonged from 1.19±1.05 h to 5.31±1.14 h with the p value of <0.0005, while the mean time of hospital stay was reduced from 22.5±3.30 h to 14.1±2.99 h with the p value of <0.0005.

Conclusion: Preemptive analgesia with 0.75% ropivacaine causes significant reduction in pain perception, request for an analgesic and hospital stay. Therefore it is advisable before inguinal hernioplasty.

Keywords: Inguinal hernioplasty; Lichtenstein mesh repair; Local anesthesia; Postoperative pain; Preemptive analgesia; Ropivacaine.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Amides*
  • Anesthetics, Local*
  • Double-Blind Method
  • Female
  • Groin / surgery
  • Hernia, Inguinal / surgery*
  • Herniorrhaphy / methods*
  • Humans
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • Nerve Block / methods*
  • Pain Perception / drug effects
  • Pain, Postoperative / drug therapy
  • Pain, Postoperative / prevention & control*
  • Prospective Studies
  • Ropivacaine
  • Surgical Mesh
  • Visual Analog Scale

Substances

  • Amides
  • Anesthetics, Local
  • Ropivacaine