Antibacterial ilicicolinic acids C and D and ilicicolinal from Neonectria discophora SNB-CN63 isolated from a termite nest

J Nat Prod. 2015 Jan 23;78(1):159-62. doi: 10.1021/np500080m. Epub 2014 Dec 5.

Abstract

Ilicicolinic acids A, C, and D (1-3) and ilicicolinal (4) were isolated from a fungus isolated from a Nasutitermes corniger nest in French Guiana. The structures of ilicicolinic acids C and D and ilicicolinal were elucidated using 1D and 2D NMR spectroscopic data as well as MS data. Ilicicolinic acids show antibacterial activity in vitro.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology*
  • Benzoates / chemistry
  • Benzoates / isolation & purification*
  • Benzoates / pharmacology*
  • Benzofurans
  • Drug Screening Assays, Antitumor
  • Female
  • French Guiana
  • Humans
  • Hypocreales / chemistry*
  • Isoptera / microbiology*
  • KB Cells
  • Molecular Structure

Substances

  • Anti-Bacterial Agents
  • Benzoates
  • Benzofurans
  • Ilicicolinic acid C
  • Ilicicolinic acid D
  • ilicicolinal