Liver disease in the adolescent

Clin Liver Dis. 2015 Feb;19(1):171-85. doi: 10.1016/j.cld.2014.09.010. Epub 2014 Nov 21.

Abstract

This article discusses common liver diseases in the adolescent. Briefly reviewed is the evaluation of the adolescent with new-onset liver enzyme elevation. Then the article discusses common liver diseases, such as nonalcoholic fatty liver disease, hepatitis, metabolic disease, biliary atresia, cystic fibrosis, and inherited disorders of cholestasis. Finally, a management approach to the adolescent with liver disease is outlined, noting the challenges that must be addressed to effectively care for not only liver disease in the adolescent but also the patient as a whole.

Keywords: Adolescent; Hepatitis; Liver disease; Nonalcoholic fatty liver disease.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Alanine Transaminase / blood
  • Biliary Atresia / complications
  • Biliary Atresia / therapy
  • Cholangitis, Sclerosing / complications
  • Cystic Fibrosis / complications
  • Glutamyl Aminopeptidase / blood
  • Humans
  • Liver Diseases / diagnosis
  • Liver Diseases / enzymology
  • Liver Diseases / etiology*
  • Liver Diseases / therapy*
  • Patient Compliance*
  • Self Care
  • gamma-Glutamyltransferase / blood

Substances

  • gamma-Glutamyltransferase
  • Alanine Transaminase
  • Glutamyl Aminopeptidase