Personality traits as predictors for the outcome of lithium augmentation in treatment-resistant depression

Michio Takahashi; Masatoshi Suzuki; Katsumasa Muneoka; Yoshiaki Tsuruoka; Koichi Sato; Yukihiko Shirayama

doi:10.1016/j.psychres.2014.09.023

Personality traits as predictors for the outcome of lithium augmentation in treatment-resistant depression

Psychiatry Res. 2014 Dec 30;220(3):1144-6. doi: 10.1016/j.psychres.2014.09.023.

Authors

Michio Takahashi, Masatoshi Suzuki, Katsumasa Muneoka, Yoshiaki Tsuruoka, Koichi Sato, Yukihiko Shirayama

PMID: 25453642
DOI: 10.1016/j.psychres.2014.09.023

Abstract

The NEO Personality Inventory-Revised (NEO) and the Temperament and Character Inventory (TCI) were administered to patients with treatment-resistant depression (n=21) before lithium augmentation. Analysis showed that the poor outcome group (n=11) had lower openness scores on the NEO, and lower cooperativeness scores on the TCI compared with the good outcome group (n=10). These findings may be predictors of poor responsiveness to lithium augmentation in the treatment of antidepressant-resistant depression.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antidepressive Agents / administration & dosage*
Antimanic Agents / administration & dosage*
Character*
Depressive Disorder, Treatment-Resistant / diagnosis
Depressive Disorder, Treatment-Resistant / drug therapy*
Depressive Disorder, Treatment-Resistant / psychology*
Drug Therapy, Combination
Female
Humans
Lithium Carbonate / administration & dosage*
Male
Middle Aged
Personality Inventory / statistics & numerical data
Psychometrics
Treatment Outcome

Substances

Antidepressive Agents
Antimanic Agents
Lithium Carbonate