Tackling infection owing to brain-eating amoeba

Acta Trop. 2015 Feb:142:86-8. doi: 10.1016/j.actatropica.2014.11.004. Epub 2014 Nov 13.

Abstract

In view of the devastating nature of primary amoebic meningoencephalitis caused by Naegleria fowleri and the problems associated with diagnostic delays and chemotherapeutic failures, here we propose a noninvasive diagnostic method using the 'reverse transcribrial route device', a novel strategy in the management of this life-threatening infection with a case fatality rate of more than 90%. The proposed rationale should stimulate interest in this emerging infection that almost always proves fatal.

Keywords: Brain-eating amoebae; Diagnosis; Management; Naegleria fowleri; Primary amoebic meningoencephalitis; Treatment.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amebiasis / diagnosis*
  • Amebiasis / parasitology
  • Amebiasis / therapy
  • Animals
  • Catheters
  • Central Nervous System Protozoal Infections / diagnosis*
  • Central Nervous System Protozoal Infections / parasitology
  • Central Nervous System Protozoal Infections / therapy
  • Equipment Design
  • Humans
  • Naegleria fowleri*
  • Nose / parasitology