Blood oxygen level dependent functional magnetic resonance imaging for presurgical planning

Meredith Gabriel; Nicole P Brennan; Kyung K Peck; Andrei I Holodny

doi:10.1016/j.nic.2014.07.003

Blood oxygen level dependent functional magnetic resonance imaging for presurgical planning

Neuroimaging Clin N Am. 2014 Nov;24(4):557-71. doi: 10.1016/j.nic.2014.07.003. Epub 2014 Nov 1.

Authors

Meredith Gabriel¹, Nicole P Brennan¹, Kyung K Peck¹, Andrei I Holodny²

Affiliations

¹ Functional MRI Laboratory, Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
² Functional MRI Laboratory, Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. Electronic address: holodnya@mskcc.org.

PMID: 25441500
DOI: 10.1016/j.nic.2014.07.003

Abstract

Functional magnetic resonance imaging (fMRI) has become a common tool for presurgical sensorimotor mapping, and is a significant preoperative asset for tumors located adjacent to the central sulcus. fMRI has changed surgical options for many patients. This noninvasive tool allows for easy display and integration with other neuroimaging techniques. Although fMRI is a useful preoperative tool, it is not perfect. Tumors that affect the normal vascular coupling of neuronal activity will affect fMRI measurements. This article discusses the usefulness of blood oxygen level dependent (BOLD) fMRI with regard to preoperative motor mapping.

Keywords: BOLD fMRI; Intraoperative motor mapping; fMRI sensorimotor mapping.

Publication types

Review

MeSH terms

Brain Neoplasms / blood
Brain Neoplasms / diagnosis*
Brain Neoplasms / surgery*
Functional Neuroimaging / methods*
Humans
Magnetic Resonance Imaging / methods*
Oxygen / blood*
Preoperative Care / methods*
Surgery, Computer-Assisted / methods*

Substances

Oxygen