Withanolides from three species of the genus Deprea (Solanaceae). Chemotaxonomical considerations

Phytochemistry. 2015 Feb:110:83-90. doi: 10.1016/j.phytochem.2014.11.015. Epub 2014 Nov 27.

Abstract

Nine withanolides were isolated from the aerial parts of Deprea bitteriana, Depreacuyacensis, and Depreazamorae. D.bitteriana yielded two withaphysalins, D. cuyacensis gave two 13,14-seco withaphysalins, while D. zamorae yielded five physangulidines. The compounds were fully characterized by a combination of spectroscopic methods (1D and 2D NMR and MS). All compounds isolated from D.bitteriana and D. cuyacensis were obtained as epimeric mixtures at C-18. The structure of physangulidine D was confirmed by X-ray diffraction analysis. The skeletons found in this research support the chemotaxonomical position of the genus Deprea in the tribe Physalideae.

Keywords: Chemotaxonomic markers; Deprea; Solanaceae; Withanolides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Colombia
  • Crystallography, X-Ray
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Components, Aerial / chemistry
  • Solanaceae / chemistry*
  • Solanaceae / classification
  • Solanaceae / genetics
  • Withanolides / chemistry
  • Withanolides / isolation & purification*

Substances

  • Withanolides