Clinical manifestations of central neurocytoma

Isaac Yang; Nolan Ung; Lawrance K Chung; Daniel T Nagasawa; Kimberly Thill; Junmook Park; Stephen Tenn

doi:10.1016/j.nec.2014.09.011

Clinical manifestations of central neurocytoma

Neurosurg Clin N Am. 2015 Jan;26(1):5-10. doi: 10.1016/j.nec.2014.09.011.

Authors

Isaac Yang¹, Nolan Ung², Lawrance K Chung², Daniel T Nagasawa³, Kimberly Thill³, Junmook Park², Stephen Tenn⁴

Affiliations

¹ Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Ste. 562, 5th Floor, Wasserman Bldg., Los Angeles, CA 90095-6901, USA. Electronic address: iyang@mednet.ucla.edu.
² Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Ste. 562, 5th Floor, Wasserman Bldg., Los Angeles, CA 90095-6901, USA; Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA.
³ Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Ste. 562, 5th Floor, Wasserman Bldg., Los Angeles, CA 90095-6901, USA.
⁴ Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA.

PMID: 25432178
DOI: 10.1016/j.nec.2014.09.011

Abstract

Central neurocytomas (CNs) are rare central nervous system tumors that occur in the lateral ventricles. They are prevalent in young adults and are typically benign with excellent prognosis following surgical resection. Because of the rarity of the disease and its similar features with more common tumors, misdiagnosis becomes an issue. Optimal treatment is achieved only when the correct tumor types are distinguished. Typical clinical manifestations include symptoms of increased intracranial pressure, although no clinical feature is pathognomonic to CN. Radiologic imaging, histology, magnetic resonance spectroscopy, and immunohistochemistry must be used to elucidate tumor characteristics and properly diagnose CN.

Keywords: Central neurocytoma; Clinical manifestation; Dissemination; Extraventricular neurocytoma; Neurocytoma.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Brain Neoplasms* / diagnosis
Brain Neoplasms* / pathology
Brain Neoplasms* / physiopathology
Humans
Neurocytoma* / diagnosis
Neurocytoma* / pathology
Neurocytoma* / physiopathology