Variable agreement among experts regarding Mycobacterium avium complex lung disease

Respirology. 2015 Feb;20(2):348-51. doi: 10.1111/resp.12440. Epub 2014 Nov 28.

Abstract

Data regarding many clinical aspects of pulmonary Mycobacterium avium complex (pMAC) are lacking. Guidelines rely substantially upon expert opinion, integrated through face-to-face meetings, variably weighting individual opinions. We surveyed North American non-tuberculous mycobacteria experts regarding clinical aspects of pMAC using Delphi methods. Nineteen of 26 invited experts (73%) responded, with extensive variability. Convergence could not be reached for most questions. Respondents described extensive uncertainty around specific issues. Findings underscore urgent need for more research.

Keywords: Delphi technique; Mycobacterium avium-intracellulare infection; mycobacterium infection; non-tuberculous mycobacterium; practice guideline.

Publication types

  • Letter

MeSH terms

  • Delphi Technique
  • Expert Testimony
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Lung Diseases / diagnosis
  • Lung Diseases / microbiology
  • Lung Diseases / therapy*
  • Mycobacterium avium Complex*
  • Mycobacterium avium-intracellulare Infection / complications
  • Mycobacterium avium-intracellulare Infection / diagnosis
  • Mycobacterium avium-intracellulare Infection / therapy*
  • North America
  • Practice Guidelines as Topic